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6-keto Prostaglandin F1α EIA Kit

Synonyms : 6-keto PGF1α ELISA Kit
Stability : 1 year
Description :
Prostacyclin (Prostaglandin I2; PGI2) is formed from arachidonic acid primarily by the vascular endothelium and renal cortex. It is a potent vasodilator and inhibitor of platelet aggregation. PGI2 is non-enzymatically hydrated to 6-keto PGF1α (t½ = 2-3 minutes), and then quickly converted to the major metabolite, 2,3-dinor-6-keto PGF1α (t½ = 30 minutes).Although 6-keto PGF1α is commonly measured in plasma and urine as an estimate of prostacyclin synthesis, it should be noted that there may be more than one source of PGI2 in these samples.Urinary concentrations of 6-keto PGF1α are confounded by the fact that some plasma prostacyclin (~14%) is excreted into urine as 6-keto PGF1α and the remainder is of renal origin. Therefore, it is important to take these factors into account when analyzing data.
Specificity :
6-keto Prostaglandin F1α 100% 
6-keto Prostaglandin E1 33.9% 
Prostaglandin F1α 28%
Storage : -20°C

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