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Ethyl malonyl chloride

Product Details

CAS: 36239-09-5
Molecular Formula: C5H7ClO3
Molecular Weight: 150.56

Product Description

Product description

Ethyl malonyl chloride Physical and chemical properties

Appearance properties: colorless or light yellow liquid
Density: 1.17
Boiling point: 79-80 º C (25 MMHG)
Refractive index: 1.425-1.431
Flash point: 67 º C
Steam pressure: 1.003mmHg at 25°C
Water solubility: react

Storage and transportation characteristics
[Storage] Keep away from heat, sparks and flames. Keep away from the source. Keep the container closed when not in use. Store in a closed container. Store in a cool, dry, well-ventilated area away from incompatible materials. Corrosive zone. Store protected moisture. Do not store in steel containers.

Storage and transportation characteristics
[Storage] Keep away from heat, sparks and flames. Keep away from the source. Keep the container closed when not in use. Store in a closed container. Store in a cool, dry, well-ventilated area away from incompatible materials. Corrosive zone. Store protected moisture. Do not store in steel containers.

Uses

pharmaceutical intermediates, Employed in the synthesis of 3-pyrrolin-2-ones via amidation with propargylamines and subsequent base catalyzed 5-exo-dig cyclization.1

Ethyl malonyl chloride is used in the syntheses of methanofullerodendimers and 3-pyrrolin-2-ones. It plays a vital role in the preparation of 3,5-disubstituted 1,2,4-oxadiazole derivatives, which are potential peptidomimetic building blocks. It is a versatile acylating agent for propargyl alcohols, hydrazines and amines.


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