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Last modified
05/26/2018 - 04:38

HDAC Cell-Based Activity Assay Kit

Product Description

Stability : 6 months
Storage : -80°C
Description :
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues and correlates with chromatin condensation and transcriptional repression. Therefore, HDAC inhibition results in transcriptional activation through the conformational relaxation of DNA.By using a cell-permeable HDAC substrate, the activity of various protein lysine-specific deacetylases including HDAC1-containing complexes can be measured in intact cells in a simple and homogenous manner. 

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