Last modified
05/26/2018 - 02:58


Product Description

CAS Number : 209783-80-2
Molecular Formula : C21H20N4O3
Formula Weight : 376.4g/mol
Stability:2 years
Formulation:A crystalline solid
Description :
MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM).1 However, it does not inhibit HDAC8 (IC50 > 100 μM).1 MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell growth, differentiation, and tumor development in vivo.23 Recent studies suggest that MS-275 may be particularly useful as an antineoplastic agent when combined with other drugs, like adriamycin,4 inhibitors of poly (ADP-ribose) polymerase (PARP),5 or inhibitors of heat shock protein 90 (Hsp90).
Storage : -20°C

Send inquiry online For more product information and prices

(Pharmaceutical Ingredients Manufacturer & Supplier & Exporter.)

After sending the online inquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email. —— Green Stone Swiss

Email: [email protected]
Tel: +86 592 5365887
WhatsApp: +86 189 6515 7632
Send inquiry online: