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Last modified
05/26/2018 - 09:00

NF-κB (p65) Monoclonal Antibody-biotin (Clone 112A1021)

Product Description

Formulation : 100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% sodium azide
Stability : 6 months
Storage : 4°C
Description :
ELISA · NF-κB regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases, and inflammation. The active nuclear form of the NF-κB transcription factor complex is composed of two DNA binding subunits, NF-κB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65. 

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