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Last modified
05/26/2018 - 02:48

Ro 31-8220 (mesylate)

Product Description

CAS : 125314-64-9
Molecular Formula : C25H23N5O2S · CH4SO3
Formula Weight : 553.7g/mol
Specification ;
Purity:≥98%
Stability:2 years
Formulation:A crystalline solid
Description :
Ro 31-8220 is a potent, cell-permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively). It is a poor inhibitor of protein kinase A (PKA, IC50 = 0.9 μM) and calcium/calmodulin kinase II (IC50 = 17 μM). Ro 31-8220 also inhibits glycogen synthase kinase 3 (IC50 = 6.8 nM).
Storage : -20°C

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