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Last modified
05/26/2018 - 08:09

SET8 (human recombinant)

Product Description

Storage : -20°C
Purity : ≥95%
Stability : 6 months
Description :
SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and transcriptional activation. SET8 is also a novel regulator of p53, mono-methylating lysine 382 of the tumor suppressor. SET8’s ability to suppress p53 transcriptional activity implies that it may play a significant role in tumorigenesis. 

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