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Last modified
05/26/2018 - 03:07

Toll-Like Receptor 8 Monoclonal Antibody (Clone 44C143)

Product Description

Stability : 1 year
Storage : -20°C
Formulation :
100 µg of protein G-purified IgG in 200 µg PBS containing 0.05% BSA and 0.05% sodium azide
Description :
The toll-like receptors (TLRs) in mammals comprise a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Like their counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition.The TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa.

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