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Last modified
05/26/2018 - 08:00

Trans-EKODE-(E)-Ib

Product Description

CAS Number : 478931-82-7
Molecular Formula : C18H30O4
Formula Weight : 310.2g/mol
Specification : 
Formulation:A solution in ethanol
Purity:≥98%
Stability:1 year
Description :
trans-EKODE-(E)-Ib is a biologically active peroxidation product of linoleic acid that is characterized, structurally, by having a trans carbon-carbon double bond between the 9-keto and 12,13-epoxy groups. It activates an antioxidant response element (ARE) in neuronal cells and induces the expression of ARE-regulated cytoprotective genes like NQO1. This EKODE also stimulates the synthesis of aldosterone and corticosterone in adrenal cells when supplied at 1-5 μM. This effect appears to be mediated by a rise in intracellular calcium. 
Storage : -20°C

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