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Last modified
05/26/2018 - 07:39

Ubiquitin Monoclonal Antibody (Clone 5B9-B3)

Product Description

Formulation :
protein G-purified IgG at a concentration of 1 mg/ml in PBS, pH 7.4, containing 50% glycerol and 0.09% sodium azide
Stability : 1 year
Storage : -20°C
Description :It is highly conserved among eukaryotic species, human and yeast ubiquitin share 96% sequence identity. The main function of ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. Ubiquitination represents an essential cellular process affected by a multi-enzyme cascade involving classes of enzymes known as ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s or Ubcs) and ubiquitin-protein ligases (E3s).Ubiquitin also plays a role in regulating signal transduction cascades through the elimination inhibitor proteins, such as IκBα and p27.

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