Last modified
05/26/2018 - 04:52

YM-58483

Product Description

CAS Number : 223499-30-7
Molecular Formula : C15H9F6N5O5
Formula Weight : 421.3g/mol
Specification : 
Purity:≥98%
Stability:2 years
Formulation:A crystalline solid
Description :
YM-58483 is a potent inhibitor of CRAC channels, blocking thapsigargin-induced sustained calcium influx, Th2 cytokine production, and NF-AT-driven promoter activity in T lymphocytes (IC50 = 100 nM). YM-58483 also inhibits lung interleukin-4 and cysteinyl leukotriene generation as well as airway eosinophil infiltration in animal models of asthma.
Storage : -20°C

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