FABP4 (human recombinant)

Product Description

Stability : 1 year
Formulation :
A solution in 50 mM of sodium phosphate, pH 7.2, containing 150 mM sodium chloride, and 20% glycerol
Description :
Fatty acid binding protein-4 (FABP4; Adipocyte-FABP) is one of nine known cytosolic fatty acid binding proteins ranging in size from 14-15 kDa containing 127-132 amino acids. Members of this protein family exhibit high affinity for small lipophilic ligands and were named according to the tissue from which they were initially isolated. Studies suggest that FABPs are involved in the uptake and metabolism of fatty acids, in the maintenance of cellular membrane fatty acid levels, in intracellular trafficking of these substrates, in the modulation of specific enzymes of lipid metabolic pathways, and in the modulation of cell growth and differentiation. Studies using FABP4 gene deletion in mice indicate a dominant role for FABP4 in several chronic metabolic diseases. Therefore, inhibiting the function of FABP4 is a potential mechanism for the treatment of metabolic diseases like diabetes and atherosclerosis.
Purity : >90%
Storage : -80°C

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