HDAC8 Inhibitor Screening Assay Kit
Synonyms : Histone Deacetylase 8 Inhibitor Screening Assay Kit
Stability : 6 months
Human HDAC8 is a class I HDAC and has been identified in a variety of human cancer tissues. Earlier studies suggested that HDAC8 localized to the nucleus and was ubiquitously expressed. Recently, it was demonstrated that HDAC8 is a novel, prominently cytosolic marker of smooth muscle differentiation and may play an important role in neuroblastoma pathogenesis. HDAC8 Inhibitor Screening Assay provides a convenient fluorescence-based method for screening HDAC8 inhibitors. The procedure requires only two easy steps, both performed in the same microplate. In the first step, the substrate, which comprises the p53 sequence Arg-His-Lys-Lys(ε-acetyl)-AMC, is incubated with human recombinant HDAC8. Deacetylation sensitizes the substrate such that treatment with the developer in the second step releases a fluorescent product. Fluorescence is then analyzed with an excitation wavelength of 350-360 nm and an emission wavelength of 450-465 nm.
Storage : -80°C
Disclaimer: the information on this website is from the internet for reference only. Please refer to the actual instructions attached to the product and the final interpretation is owned by the company.
Send inquiry online For more product information and prices
(Pharmaceutical Ingredients Manufacturer & Supplier & Exporter.)
After sending the online inquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email. —— Green Stone SwissEmail: email@example.com
Tel: +86 592 5365887
WhatsApp: +86 189 6515 7632
Send inquiry online: