Interleukin-1β (human) EIA Kit

Product Description

Synonyms : IL-1β (human) ELISA Kit 
Stability : 6 months
Description:IL-1β is synthesized as 269 amino acid pro-cytokine that is enzymatically cleaved by IL-1β-converting enzyme (ICE) into the active 154 amino acid, 17 kDa peptide mature peptide. IL-1β is produced by many cell types including macrophages, monocytes, astrocytes, endothelial cells, smooth muscle cells, keratinocytes, adipocytes, T cells, and eosinophils. Although IL-1α and IL-1β exhibit only 26% amino acid identity, they bind to the same cell-surface receptors, IL-1 RI and IL-1 RII, present on a variety of cell types involved in immune or inflammatory responses. Normal production of IL-1 is critical for mediating host responses to infection and injury. Disease states in which IL-1 actively participates include inflammatory diseases, such as arthritis, inflammatory bowel disease, and shock, as well as arteriosclerosis, allergic disease, and some types of cancer.
Specificity :
Interleukin-1β 100% 
Interleukin-1α <0.01% 
Interleukin-2 <0.01%
Storage : -20°C

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