FABP1 (human recombinant)
A solution in 50 mM sodium phosphate, pH 7.2, containing 25% glycerol and 100 mM sodium chloride
Description:FABP family members have highly conserved three dimensional structures and 22-73% amino acid sequence similarity. FABP1 is composed of ten antiparallel β strands that form a barrel and have a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acids into its binding pocket. Expression of FABP1 is decreased in hepatoblastoma and hepatocellular carcinoma making the protein a potential tumor marker. Moreover, studies have suggested FABP1 as a potential biomarker for both liver and kidney injury.
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