Prostaglandin F Synthase (human recombinant)
Stability : 6 months
A solution in 100 mM sodium phosphate, pH 7.2, containing 20% glycerol, 100 mM sodium chloride, and 1 mM EDTA
Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence similarity to aldo-keto reductase family members. It exhibits two related primary activities, catalyzing the isomerization of PGH2 to PGF2α (PGH2 9,11-endoperoxide reductase activity), as well as the formation of 11β-PGF2α from PGD2 (PGD2 11-ketoreductase activity) in the presence of NADPH. The enzyme also exhibits reductase activities toward carbonyl compounds such at nitroacetophenone, nitrobenzaldehyde, and 9,10-phenanthrene quinine (PQ).
Purity : >90%
Storage : -80°C
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