Prostaglandin F2α EIA Kit

Synonyms : PGF2α ELISA Kit
Stability : 1 year
Description :
Prostaglandin F2α (PGF2α) is one of the five primary PGs derived enzymatically directly from the endoperoxide PGH2. It was initially discovered in seminal fluid, and to date the majority of the functional roles ascribed to it relate to fertility, pregnancy, and parturition. PGF2α is a potent luteolytic agent and is used to induce ovulation in domestic livestock. It is also a potent uterine stimulant, and is part of the cascade of myometrial stimulants which induce and sustain labor. PGF2α is rapidly metabolized to 13,14-dihydro-15-keto PGF2α in vivo, and the levels of this metabolite in both plasma and amniotic fluid are elevated during active labor in several different mammalian species. Like all of the primary PGs, PGF2α has a very short half-life in the general circulation. The plasma concentration of PGF2α in humans is <10 pg/ml, and probably no more than 1-2 pg/ml.1 PGF2α is rapidly metabolized by 15-hydroxy PG dehydrogenase and both β- and ω-oxidation systems to a variety of polar metabolites.
Specificity :
Prostaglandin F2α Ethanolamide 244.1% 
Prostaglandin F2α 100% 
Prostaglandin F1α 61%
Storage : -20°C