Calcium-D-Glucarate Sources & Structure
Sources
Calcium-D-Glucarate is a calcium salt of the molecule known as D-Glucaric acid (also known as Saccharic acid), an endogenously produced acid via D-glucuronic acid that also appears to be found in fruit and vegetable food products with high levels in oranges, apples, grapefruit, and cruciferous vegetables. As D-glucaric acid is the main bioactive, any dietary supplement conferring it can be of similar benefit (including potassium hydrogen D-glucarate).
It is thought that glucaric acid is chemoprotective, and it has been noted that in cohorts of smokers with indicators of DNA damage (K-ras mutations) that circulating glucaric acid is 34% lower.
Glucaric acid, supplemented via its calcium salt (Calcium-D-Glucarate), is thought to be a chemoprotective and anti-toxin compound
Specific concentrations of glucaric acid found in food products include:
- Peeled oranges at 4.63+/-0.58mg/100g
- Carrots at 2.45+/-0.32mg/100g
- Spinach at 1.58+/-0.35mg/100g
- Apples at 1.57+/-0.09mg/100g
- Broccoli at 1.32+/-0.23mg/100g
- Alfalfa sprouts at 0.82+/-0.06mg/100g
- Peeled potatoes at 0.74+/-0.08mg/100g
Oranges appear to be the highest known source, followed by applies and broccoli. Admittedly, however, not many food products appear to have been tested for the presence of glucaric acid salts
Structure
As calcium-D-glucarate is a calcium salt of D-glucaric acid, it is simply the structure of each individual molecule. Other molecules that also confer D-glucarate (such as potassium hydrogen D-glucarate) confer similar properties to the body.

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