What is Povidone-iodine (PVP-I)?

Povidone-iodine (PVP-I), cast name Wokadine, Pyodine, and Betadine is a abiding actinic circuitous of polyvinylpyrrolidone (povidone, PVP) and basal iodine. It contains from 9.0% to 12.0% accessible iodine, affected on a dry basis.
This different circuitous was apparent in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. They agitated out tests in vitro to authenticate anti-bacterial activity, and begin that the circuitous was beneath baneful in mice than blush of iodine. Human analytic trials showed the artefact to be above to added iodine formulations. It was anon marketed, and has back become the universally adopted iodine antiseptic.