Last modified
08/13/2018 - 06:33

What is Prostaglandin?

Prostaglandin is any affiliate of a accumulation of physiologically alive compounds acquired from unsaturated 20-carbon polyunsaturated blubbery acids, primarily arachidonic acid. Prostaglandins are lipids accepting two continued ancillary chains and a 5 carbon ring structure. They are begin in accustomed animal berry in accomplished concentrations. Their activities affect the afraid system, circulation, changeable changeable organs, and metabolism agnate to bounded hormone functions But they are not classified in hormones. 
Prostaglandin belongs to eicosanoids, biologically alive 20-carbon substances including prostaglandins, thromboxanes, prostacyclins, and leukotrienes. Eicosanoids are oxygenated berserk cytokines, baby proteins that are the amount of advice amid allowed systems. Prostaglandins, thromboxanes, prostacyclins are acquired via the cyclooxygenase pathway, while leukotrienes are via 5-lipoxygenase pathway. Prostaglandins are eicosanoids accepting a cyclopentane ring. Prostaglandins accept two bifold bonds typically, while leukotrienes accept four. 
Prostaglandins act in the beef in which they are actinic and surrounding cells, and their accomplishments and furnishings alter with concentration, hormonal environment, and corpuscle type. Prostaglandins arbitrate a advanced ambit of physiological functions, such as ascendancy of claret pressure, adjustment of muscle, glandular secretion, manual of assumption impulses, and accentuation of inflammation. Specific Prostaglandins appointed by abacus a letter on PG (the abridgement for prostaglandin) to announce the blazon of ring anatomy and a after subscript to announce the amount of bifold bonds. The subscript alpha or beta indicates the three-dimensional agreement of alcoholic groups absorbed to the ring structures. Alpha denotes a substituent beneath the even of the ring, beta, aloft the plane. 
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Prostaglandin E1

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