what is Trimethylsulfoxonium iodide
Trimethylsulfoxonium iodide is a sulfoxonium salt. It is acclimated to accomplish dimethyloxosulfonium methylide by acknowledgment with sodium hydride.This admixture is commercially available. The closing admixture is acclimated as a methylene-transfer reagent, and is acclimated to adapt epoxides.
Trimethylsulfoxonium iodide is advantageous for advancing ylides in able abject condition. The Treatment with able abject (such as sodium hydride) yields the ylide which adds to the carbonyl accumulation of ketones and aldehydes to accomplish the Corey-Chaykovsky reagent . Also cyclopropanation can be agitated out in ionic liquids with top yields preferentially to the bifold band of alpha,beta-unsaturated esters to accord cyclopropyl esters.
Treatment with able abject yields the ylide which adds to the carbonyl accumulation of ketones and aldehydes to accord epoxides. Also adds preferentially to the bifold band of α,β-unsaturated esters to accord cyclopropyl esters.
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