HDAC6 (human recombinant)

Formula Weight : 159.0g/mol
Stability : 6 months
Formulation :
50 µg in 25 mM Tris-HCl, pH 8.0, containing 138 mM sodium chloride, 0.05% Tween 20, and 10% glycerol
Description :
HDAC6 is a Class II HDAC that can shuttle between the nucleus and cytoplasm, suggesting potential extranuclear functions by regulating the acetylation status of non-histone substrate. By modifying chromatin structure and other non-histone proteins, HDACs play important roles in controlling complex biological events, including cell development, differentiation, programmed cell death, angiogenesis, and inflammation. Considering these major roles, it is conceivable that dysregulation of HDACs and subsequent imbalance of acetylation and deacetylation may be involved in the pathogenesis of various diseases, including cancer and inflammatory diseases.
Purity : >80%
Storage : -80°C