SIRT2 (human recombinant)

Stability : 9 months
Formulation :
50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol
Description :
SIRT2 is a cytoplasmic protein responsible for the deacetylation of histone H4 and a-tubulin, a modification important for controlling the cell cycle. Specifically, SIRT2 co-localizes with HDAC6 and microtubules and functions as a mitotic checkpoint in preventing chromosomal instability that can lead to hyperpolid cells. SIRT2 is found in many tissues, but is specifically enriched in skeletal muscle, the heart, and in oligodendroglia cells in the brain.
Purity :  ≥90%
Storage : -80°C