SIRT6 (human recombinant)

Stability : 6 months
Formulation :
25 mM Tris, pH 8.0, containing 100 mM sodium chloride and 20% glycerol
Description:
SIRT6 associates specifically with telomeres and functions at chromatin to decrease NF-κB signaling. Mammalian cells depleted of SIRT6 display abnormal telomere structures similar to defects found in Werner syndrome, a premature ageing disorder, and have a shortened life span. Since SIRT6 binds and attenuates NF-κB signaling, it is proposed that activators of SIRT6 may be effective anti-cancer and anti-inflammatory drugs and may increase longevity.
Purity  : >95%
Storage : -80°C