Which is better between Tadalafil (Cialis) VS Sildenafil (Viagra).

Which pharmaceutical ingredients better, let's look at a few aspects, in turn, compare the efficacy, long time efficacy, side effects, you naturally have the answer.

Tadalafil (Cialis) and Sildenafil (Viagra)  of function

Tadalafil (Cialis) and Sildenafil (Viagra) are phosphodiesterase-5 (PDE5) inhibitors used for treating impotence (erectile dysfunction, or ED).

What are the side effects of Sildenafil and Tadalafil?

Tadalafil

The most common side effects of tadalafil are:

• facial flushing (reddening),
• headaches,
• stomach upset,
• diarrhea,
• flu-like symptoms, and
• nausea.
• Tadalafil also may cause low blood pressure,
• blurred vision,
• changes in color vision, and
• abnormal ejaculation.

Sildenafil

Approximately 15% of persons taking Viagra experience side effects. The most common side effects are:

• facial flushing (1 in 10),
• headaches (1 in 6),
• stomach pain,
• nasal congestion,
• nausea,
• dizziness,
• rash,
• urinary tract infections (UTIs)
• diarrhea, and
• an inability to differentiate between the colors green and blue.

Tadalafil, sildenafil, all act by inhibiting the PDE5 enzyme. These drugs also inhibit other PDE enzymes. Sildenafil inhibit PDE6, an enzyme found in the eye, more than tadalafil.Some sildenafil users see a bluish tinge and have a heightened sensitivity to light because of PDE6 inhibition.Sildenafil also inhibit PDE1 more than tadalafil. PDE1 is found in the brain, heart, and vascular smooth muscle. It is thought that the inhibition of PDE1 by sildenafil leads to vasodilation, flushing, and tachycardia. Tadalafil inhibits PDE11 more than sildenafil.PDE11 is expressed in skeletal muscle, the prostate, the liver, the kidney, the pituitary gland, and the testes. The effects on the body of inhibiting PDE11 are not known.

What is the dosage of Tadalafil (Cialis) VS Sildenafil (Viagra)?

Tadalafil

• For most individuals, the recommended starting dose of tadalafil is 10 mg per day taken before sexual activity (tadalafil for use as needed).
• Depending on the adequacy of the response or side effects, the dose may be increased to 20 mg or decreased to 5 mg a day. The effect of tadalafil may last up to 36 hours. Individuals who are taking medications that increase the blood levels of tadalafil should not exceed a total dose of 10 mg in 72 hours (See drug interactions). For once daily use without regard to sexual activity the recommended dose is 2.5 to 5 mg daily. Tadalafil should not be taken more than once daily.
• The recommended dose for BPH, or BPH and ED is 5 mg daily taken about the same time each day. Tadalafil may be taken with or without food since food does not affect its absorption from the intestine.
• The dose of tadalafil may require adjustment for patients with reduced kidney or liver function.

Sildenafil

• The usual recommended dose is 25 to 100 mg 1 hour before sexual activity.
• The maximum dose is 100 mg daily.
• The elderly (over 65 years of age) should start at 25 mg before sexual activity.
• Sildenafil is rapidly absorbed. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. When sildenafil is taken with a high-fat meal, the rate of absorption is reduced, with an average delay in the time to maximal concentration of 1 hour.

Sildenafil (Viagra) can be effective in as little as 1 hour, while Cialis might not take effect for 2 hours, though for some patients these medicines can work more rapidly. In fact, Tadalafil (Cialis) might work in as few as 30 minutes and some patients find that Sildenafil (Viagra) can start to have an effect in 15 minutes. Nevertheless, each should be approached as reliably taking effect in 1 hour for Viagra and in 2 hours for Cialis.

Viagra leaves the body in about 6 to 8 hours, while Cialis can work for 24 to 36 hours. That means that while they are both very effective–approximately 75% of patients will achieve a satisfactory erection with either–Viagra (sildenafil) will work reliably for 6-8 hours but Cialis (tadalafil) will work for up to 36 hours. Nevertheless, the effect of a medication may not be needed beyond 6 or 8 hours, and any side effects (in addition to any positive effect) they cause will fade rapidly as the medication leaves the bloodstream. That means that someone who experiences nasal congestion or flushing when they use either Cialis (tadalafil) or Viagra (sildenafil) may find it useful to take the shorter acting medication, Viagra (sildenafil). It might be worth a bit of nasal congestion during the time when sex will occur but there would be no reason to endure a stuffy nose once sexual intimacy had concluded.

Again, it is never as simple as considering just one factor. There is a good deal of trial and error in finding the right medicine, the most effective dose, and the plan that results in the fewest side effects. Sometimes, a side effect is worth the benefit, sometimes not. On occasion, a man will be on medications that require a dose adjustment. Even a simple antibiotic like erythromycin can alter how the body handles either medication and the dose must be adjusted. Grapefruit juice can do so as well. Some medications lower blood pressure and each of these medications, Viagra or Cialis, can add to that blood pressure lowering effect and be quite dangerous. Nitrates, nitrites, and nitroglycerin can all be dangerous when combined with medications that treat erectile dysfunction.

Now, I believe that in combination with your own situation, it should be clear which is better between Tadalafil (Cialis) VS Sildenafil (Viagra).

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