|Alias||5-Ureidohydantoin; Glyoxyldiureide; 1-(2,5-dioxoimidazolidin-4-yl)urea|
|Appearance||White crystalline powder|
Allantoin is a chemical compound with formula C4H6N4O3. It is also called 5-ureidohydantoin or glyoxyldiureide. It is a diureide of glyoxylic acid. Allantoin is a major metabolic intermediate in most organisms including animals, plants and bacteria. It is produced from uric acid, which is a degradation product of purine nucleobases, by urate oxidase (or uricase).
A kind of avirulent, insipidity, without excitant, white crystal without allergic, the water of crystallization for single prism or colorless crystalline powder. Soluble in hot water, heat and dilute sodium hydroxide solution. Slightly soluble in cold water and alcohol, soluble in ether and chloroform and other organic solvents; Odorless and tasteless. Stable in dry air, boiled in water for a long time or destroyed in strong alkali. The saturation concentration (0.6%) is slightly acidic aqueous solution; PH 5.5.It is also called 5-ureidohydantoin or glyoxyldiureide.
Allantoin has long been used for its healing, soothing, and anti-irritating properties. Allantoin helps to heal wounds and skin irritations and stimulates the growth of healthy tissue. Allantoin can be found in anti-acne products, sun care products, and clarifying lotions because of its ability to help heal minor wounds and promote healthy skin. Allantoin is frequently present in toothpaste, mouthwash, and other oral hygiene products as well as in shampoos, lipsticks, various cosmetic lotions and creams, and other cosmetic and pharmaceutical products.
Manufacturers cite several beneficial effects for allantoin as an active ingredient in over-the-counter cosmetics, including: a moisturizing and keratolytic effect, increasing the water content of the extracellular matrix and enhancing the desquamation of upper layers of dead skin cells, increasing the smoothness of the skin, and a soothing, anti-irritant, and skin protectant effect by forming complexes with irritant and sensitizing agents.
Allantoin protein can be formulated into a scalp preparation that is anti-irritant, anti-dandruff, cleansing and healing the wound, making the hair soft, shiny and elastic. The product is an amphoteric compound, which can be combined with various substances to form a salt. It has the functions of protecting against a light, sterilizing, antiseptic, analgesic, deodorizing and anti-oxidation. Therefore, it is a daily chemical product, a cosmetic such as a freckle cream, acne powder, shampoo. Additives such as soap, toothpaste, shave lotion, astringent, anti-sweat deodorant detergent, etc. Allantoin is also a biochemical reagent.
Allantoin has anti-inflammatory and analgesic effects, and it also has a weak local paralysis effect, which can effectively alleviate the stimulation of irritants. It can be used as a skin protectant and anti-irritant to reduce the irritation of cosmetic ingredients on the skin. The Food and Drug Administration lists it as the first class of high-efficiency sub-component skin care agents, which are now widely used in shampoos, sunscreen products, cream lotions, shaving creams, and oral care products.
- Cosmetics and toiletries
Manufacturers cite several beneficial effects for allantoin as an active ingredient in over-the-counter cosmetics, including: a moisturizing and keratolytic effect, increasing the water content of the extracellular matrix and enhancing the desquamation of upper layers of dead skin cells, increasing the smoothness of the skin; promoting cell proliferation and wound healing; and a soothing, anti-irritant, and skin protectant effect by forming complexes with irritant and sensitizing agents.
It is frequently present in toothpaste, mouthwash, and other oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions, various cosmetic lotions and creams, and other cosmetic and pharmaceutical products.
- Biomarker of oxidative stress
Since uric acid is the end product of the purine metabolism in humans, only non-enzymatic processes with reactive oxygen species will give rise to allantoin, which is thus a suitable biomarker to measure oxidative stress in chronic illnesses and senescence.
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