|Usage||Cosmetics / Pharmaceuticals|
|Appearance||Colorless rhomboid crystal|
Benzocaine is a fat-soluble topical anesthetic or cough drops that are less potent than several other local anesthetics such as lidocaine and dicaine, Therefore when it acts on the mucous membrane, it does not cause discomfort due to anesthesia. It is a lot of non-prescription anesthetic cream active ingredient.
benzocaine as colorless rhombic crystals, odorless, soluble in alcohol, ether, chloroform. It can be dissolved in almond oil, olive oil, dilute acid. Hard to dissolve in water. Clinically for wounds, ulcers, burns, cracked skin and rub analgesic hemorrhoids, itching.
The local use of benzocaine acts on the nerve tissue of the skin and mucous membranes blocks the conduction of nerve impulses, temporarily loses various sensations, and paralyzes the nerve endings to produce analgesia and antipruritic effects. The local anesthetic effect of benzocaine is weaker than procaine, and it can be absorbed slowly for external use. It has a long-lasting effect and has analgesic and antipruritic effects. The toxicity of benzocaine is only 1/20 to 1/160 of cocaine. It is a fat-soluble drug, so it is easy to combine with the mucous membrane of the mucous membrane or skin, but it is not easy to penetrate and enter the body to produce toxicity.
Pain is caused by the stimulation of free nerve endings. When the nerve endings are stimulated, sodium enters the neurons, causing the depolarization of the nerves and the subsequent initiation of action potentials. The action potential travels along the nerve to the central nervous system, interpreting it as pain. Benzocaine is used to inhibit voltage-dependent sodium channels (VDSC) on neuronal membranes, preventing the spread of action potentials.
Benzocaine can be used as a precursor material for Osso, Ozocaine, Procaine;
Meanwhile, it is used in medicine and a local anesthetic, analgesic, antipruritic effect, mainly for wounds, ulcers, mucosal surface
Narcotic analgesics and hemorrhoids and itch, which may also serve as an ointment nasopharyngeal catheter, endoscope within the sudden pain and other lubrication.
Temporary relief of pain and itching of the skin discomfort, minor burns, sunburn, wounds and insect bites.
The otic preparation is used to alleviate the pain and itching of the acute congestive, concentrated otitis externa, swimming ear inflammation and external use of the ear.
Benzocaine for toothache, sore throat, mouth ulcers, a variety of hemorrhoids, anal fissure, vulvar itching also effective, as a male genital desensitizing agent to slow ejaculation. Or as an anesthetic lubricant for catheters and endoscopes.
Benzocaine is indicated for the treatment of a variety of pain-related diseases. It may be used to:
UV absorber. It is mainly used in sunscreen and tanning cosmetics. It is chemically stable to light and air, safe to the skin, and has the ability to form a film on the skin. It can effectively absorb ultraviolet rays in the 280-320μm medium-wave region of the U.V.B region. The amount added is usually about 4%.
- Also used as an intermediate in pharmaceutical synthesis and organic synthesis.
- Local anesthesia of the oral and pharyngeal mucosa (sore throat, cold sore, mouth ulcers, toothache, gum pain, denture stimulation)
- Earache (ear pain)
- Surgical or surgical local anesthesia
- Some glycerin-based ear medications are used to remove excess wax and to relieve ear diseases such as otitis media and swimmers' ears.
- Some condoms are designed to prevent premature ejaculation.
- Benzocaine mucoadhesive patches have been used to reduce orthodontic pain.
- In Poland, it is included with menthol and zinc oxide in liquid powders that are primarily used for mosquito bites (not to be confused with liquid powders).
Benzocaine hydrochloride is the hydrochloride salt form benzocaine, with pharmacological effects of benzocaine, procaine weaker than the effect of anesthesia.
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