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Last modified
10/23/2018 - 07:13

GP4G(Plankton Extract)

Product Details

Name GP4G
Alias Diguanosine tetraphosphate
INCI Name ARTEMIA EXTRACT
CAS  No. 102783-33-5
Category Extract
Weight 868.39 g/mol
Usage Cosmetic / Skin Care 
Appearance Powder/liquid

Product Description

GP4G (Diguanosine tetraphosphate) is a unique marine plankton extract.

Function

1.Cell Protection Factor

  • Cell: human keratinocytes Addition: 1%GP4G

Conclusion GP4G protects and repairs DNA damage in skin cells.

Conclusion: GP4G protects and repairs DNA damage in skin cells.

 

  • Comet Assay: Cell: human fibroblast       Addition: 3%GP4G

Action time: 48h                            UVB dosage:  30mJ/cm2

Cells treated with GP4G have very little DNA damage relative  to untreated cells.

Conclusion: Cells treated with GP4G have very little DNA damage relative to untreated cells.

 

  • End-labelling Technique:

Cell: human keratinocytes       Addition: 1%GP4G

Conclusion: GP4G protects and repairs DNA damage in skin cells.

Conclusion: GP4G protects and repairs DNA damage in skin cells.


2.Cell Energy Factor

At the beginning of the fairy shrimp was awakened, it was observed that the GP4G content in the fairy shrimp decreased rapidly, and ATP increased rapidly.

the GP4G content in the fairyshrimp decreasedATP increased rapidly

Conclusion: GP4G is a stable precursor of ATP, and GP4G is directly converted to ATP.


3.Cell Activation Factor

  • The immunoblotting technique (keratin) and the immunofluorescence technique (filaggrin)

Cell: human keratinocytes       Addition: 1%GP4G

Total keratins (pixels)

Conclusion: GP4G enhances the synthesis of proteins that play a key role in the epidermis.

  • The immunoblotting technique (keratin) and the immunofluorescence technique (filaggrin)

gp4g observation group

 

  • The immunoblotting technique

Cell:human fibroblasts                       Addition: 1%GP4G

Total extracted cell proteinsIntensity (% of increase/control)

Conclusion: GP4G enhances the synthesis of proteins that play a key role in the dermis.


4.Cell Defense Factor

GP4G promotes the production of HSP70 and plays an important role in the metabolism of many cells.

 Heat shock protein is a protective protein. When the body is attacked by harsh environments such as high temperatures, a large amount of heat shock protein is synthesized, which helps each cell maintain normal physiological activities, prevent protein interactions that affect cell health and allow the physiological processes in the cells to operate smoothly.

Cell Defense Factor

When the cells are subjected to great environmental stress, it will immediately synthesize more heat shock proteins. Heat shock proteins (HSP) play an important role in protecting cells against various types of damage.

Heat shock proteins (HSP) play an important role in protecting cells against various types of damage.


5. Cell Antiallergic Factor

ELISA Test
Cell: HaCaT cell     Addition: 3%GP4G     UVB dosage: 30mJ/cm2

pg IL-1 alpha/mg proteins

Conclusion: GP4G reduces UV-induced pro-inflammatory cytokines synthesis.


 

Application

1.Sunscreen products
2.Newborn empowerment products
3.Anti-photoaging products
4.Repair DNA products
5.Hair care product
 

Instruction for Use
 

●Concentration 160-200ppm, addition 0.5-5%

●Concentration300-360ppm, addition 0.3-3%

●Keep in dry, cool and dark place

●Valid period: two years
 

 

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