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Last modified
05/26/2018 - 02:54

Toll-Like Receptor 2 Monoclonal Antibody (Clone TL2.1)

Product Description

Stability : 1 year
Storage : -20°C
Formulation :
100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium salt
Description :
The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Most mammalian species have between ten and fifteen types of TLRs. Ten functional TLRs (TLR1-10) have been identified in human.TLR2 is differentially expressed in human cells. Historically speaking, TLR expression has been most extensively studied in the immune system. Overall, TLRs are highly expressed in immune competent cells, including macrophages, dendritic cells, neutrophils, mucosal epithelial cells, and dermal endothelial cells. However, TLRs have also been identified in many other cell types and anatomical tissue locations where they are expressed either constitutively or induced during infection. 

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