15-hydroxy Prostaglandin Dehydrogenase (human recombinant)

Product Description

CAS : 78028-01-0 
Molecular Formula : C17H16N2O5
Formula Weight : 328.32g/mol
Stability : 6 months
Formulation :
A solution in 50 mM Tris-HCl, pH 7.5, containing 1 mM EDTA, 1 mM DTT, and 30% glycerol
Description :
Human NAD+-dependent 15-PGDH is a 266 amino acid protein with a molecular weight of 29 kDa and is expressed in multiple tissues including lung, placenta, and kidney. The enzyme belongs to a large family of short-chain alcohol dehydrogenases, which exhibit amino acid identity ranging from 15-30%.3,4 Recent studies indicate 15-PGDH may play a role as a tumor suppressor. Studies have shown an inverse correlation between 15-PGDH expression and cell proliferation in colon, breast, and thyroid cells. 15-PGDH specific activity was determined using PGE2 as the substrate and NAD+ as the cofactor and was calculated after subtracting the mass contribution form the GST tag. The reaction was inhibited using CAY10397. 
Purity : >95% by SDS-PAGE
Storage : -80°C

Send inquiry online For more product information and prices

(Pharmaceutical Ingredients Manufacturer & Supplier & Exporter.)

After sending the online inquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email. —— Green Stone Swiss

Email: [email protected]
Tel: +86 592 5365887
WhatsApp: +86 189 6515 7632
Send inquiry online: