L-Carnitine's impact on the heart

L-carnitine is an amino acid solution that performs three very important functions that enhance athletic performance:

L-carnitine is THE nutrient, the "ferry" so to speak, that shuttles fatty acids from the blood to the mitochondria, the energy producing "furnaces" in the cells, so that the fat can be used as energy. If you want to use fat as a fuel as proficiently and effectively as possible, you need l-carnitine.
L-carnitine also helps improve endurance by suppressing the build-up of lactic acid, one of the primary causes of exhaustion.
L-carnitine has also recently been shown to reduce the accumulation of metabolic wastes during exercise. This helps increase workload output during exercise and boosting healing post-exercise.
Necessary for athletic performance, heart health, and more

L-carnitine is an organic compound found in food. Yet, it is not considered an essential nutrient because the body can make it from the amino acids lysine and methionine. L-carnitine is the nutritional that transports essential fatty acids to the mitochondria for proper use as a fuel source and research shows that muscle carnitine levels are swiftly depleted during exercise, even moderate exercise. A number of published studies on athletes show that l-carnitine supplementation supports exercise performance. Athletes need to know more carnitine than they are capable of producing endogenously (inside the body). L-carnitine may be especially important during periods of intense exercise as it can help to reduce post-exercise lactic acid accumulation and may increase maximal work end result. It can possibly preserve muscle glycogen levels during workouts. Since reported in the the greater part of studies, a rise in maximum oxygen consumption and a lowering of the respiratory quotient indicate that nutritional l-carnitine has the potential to stimulate lipid metabolism (e. g. the utilization of fat for fuel). Remedy with l-carnitine has also been shown to stimulate a substantial post-exercise reduction in plasma lactate, which is created and used consistently under fully aerobic conditions. Data from preliminary studies have indicated that l-carnitine supplements can attenuate the unhealthy associated with hypoxic (low oxygen) training and speed upwards recovery from exercise stress. Recent data have suggested that l-carnitine plays a decisive role in the prevention of cellular destruction and favorably impacts healing from exercise stress. Additionally, among its other benefits for brain, body composition, and mitochondrial health, l-carnitine is important for normal heart to perform.

cent study poses questions

Recently, there has been some negative press on l-carnitine in the information. In a nutshell, the results of the study, posted online in the record Nature Medicine, suggest that orally dosed l-carnitine is metabolized by intestinal bacteria to produce a compound called trimethylamine (TMA). TMA is possibly further metabolized into trimethylamine-N-oxide (TMAO). It is theorized that TMAO prevents of excess bad cholesterol from being excreted, thus allowing it to infiltrate artery walls, which will be studied as a possible culprit for increased chance of cardiovascular disease. Noises somewhat scary, doesn't it? But does that imply that l-carnitine supplementation puts you at risk?

A few take a closer look at l-carnitine in common, and also this recent study and its implications. First, however, it's important to keep in mind the axiom, 'If a little is good, a lot is not necessarily better. ' Also basic substances required for life can be overdosed or underdosed, contributing to damaging life-threatening consequences. For example:

Water depletion/dehydration can eliminate you, but too much water ("water Intoxication") is also lethal.
Too little sodium is known as hyponatremia, a life-threatening crisis. An excessive amount of sodium results in hypernatremia, which also has potentially fatal consequences.
Also much sugar or carbs has been associated with diabetic issues, yet when the blood glucose proceeds is excessive, consuming sugars during exercise is safe and recommended.
So what does this particular examine mean for me?

While this study is certainly intriguing, it's important to keep in mind that the study subjects (both humans and mice) were given "chronic" amounts of l-carnitine. While we do not know how much was given to these test subjects, previous research done on humans suggests that a very large amount of l-carnitine (6 grams total/day) is required for significant boosts of plasma TMAO. Additional dosages administered three times daily (a total of 0. 0g, 1. 5g, and 3g total each day) showed no change in plasma increases of TMAO. REFERENCE: Bain MOTHER, Milne RW, Evans FEEL. J Clin Pharmacol. 06\ Oct; 46(10): 1163-70. Predisposition and metabolite kinetics of oral L-carnitine in humans. Sansom Institute, School of Pharmacy and Medical Savoir, University of South Quotes, Adelaide, SA 5000, Sydney.

Conclusion

Athletes can properly consume l-carnitine in health supplement form to justify substitute. If you are eating supplemental l-carnitine, we recommend keeping your totals in the range of 2000 mg (2g) per day. A non-athlete who consumes large amounts of lean meats that contain l-carnitine does not supplement this substance. Creature meat not only creates bodily carnitine, it also generates a protein construction that drives weight gain, growth factors, and back plate formation. If not derived from naturally raised grass-fed pets, there are other damaging substances found in meats that over time may prove harmful to health. Total, we recommend not overconsuming substances from the animal kingdom that drive hypercholesteria accumulation on artery surfaces.